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研究業績

Original Papers

    1. *Hui Zhang, Naoki Kikuchi, Noriyasu Ohshima, Taira Kajisa, Toshiya Sakata, Takashi Izumi, and Hayato Sone, “Design and Fabrication of Silicon Nanowire-Based Biosensor with Integration of Critical Factors: Toward Ultrasensitive Specific Detection of Biomolecules” ACS Appl. Mater. Interfaces, accepted, (2020).
    2. Masakazu Aihara, Naoto Kubota*, Takahiro Minami, Rika Shirakawa, Yoshitaka Sakurai, Takanori Hayashi, Masahiko Iwamoto, Iseki Takamoto, Tetsuya Kubota, Ryo Suzuki, Satoshi Usami, Hideaki Jinnouchi, Makoto Aihara, Toshimasa Yamauchi, Toshiya Sakata*, and Takashi Kadowaki*, “Association between tear and blood glucose concentrations: random intercept model adjusted with confounders in tear samples negative for occult blood” Journal of Diabetes Investigation, , (2020). (DOI: 10.1111/jdi.13344)
    3. *Toshiya Sakata, Masami Hagio, Akiko Saito, Yuto Mori, Masayuki Nakao, and Kazuhiko Nishi, “Biocompatible and flexible paper-based metal electrode for potentiometric wearable wireless biosensing” Sci. Technol. Adv. Mater., 21, (2020), 379-387. (DOI: 10.1080/14686996.2020.1777463)
    4. *Toshiya Sakata, Shoichi Nishitani, and Taira Kajisa [Review Article] “Molecularly imprinted polymer-based bioelectrical interface with intrinsic molecular charges” RSC Advances, 10, (2020), 16999-17013. (DOI: 10.1039/D0RA02793F)
    5. Shoichi Nishitani and *T. Sakata “Enhancement of signal-to-noise ratio for serotonin detection with well-designed nanofilter-coated potentiometric electrochemical biosensor” ACS Appl. Mater. Interfaces, 12, (2020), 14761-14769. (DOI: 10.1021/acsami.9b19309)
    6. Toru Fukuma, Shoichi Nishitani and *T. Sakata “Functionalization of Polymeric Nanofilter Biointerface for Small Biomarker Sensing” ECS Trans., 97, (2020), 9-14. (DOI: 10.1149/09706.0009ecst)

2019

    1. Hiroto Satake and *Toshiya Sakata Estimation of extracellular matrix production using cultured-chondrocyte-based gate ion-sensitive field-effect transistor Analytical Chemistry, 91 (2019), 16017-16022. (DOI: 10.1021/acs.analchem.9b04789)
    2. Kensuke Ito, Hiroto Satake, Yuto Mori, Alex C. Tseng, and *Toshiya Sakata Biocompatible and Na+-sensitive thin-film transistor for biological fluid sensing Sci. Technol. Adv. Mater., 20(1), (2019), 917-926. (DOI: 10.1080/14686996.2019.1656516)
    3. Hiroto Satake and *Toshiya Sakata Interfacial pH Behavior at Cell/Gate Insulator Nanogap Induced by Allergic Responses ACS Omega, 4(10), (2019), 14255−14260. (DOI: 10.1021/acsomega.9b01872)
    4. Haoyue Yang and *T. Sakata Molecular-Charge-Contact-Based Ion-Sensitive Field-Effect Transistor Sensor in Microfluidic System for Protein Sensing Sensors, 19(15), (2019), 3393. (DOI: 10.3390/s19153393)
    5. *T. Sakata [Perspective] “Biologically coupled gate field-effect transistors meet in vitro diagnostics” ACS Omega, 4(7), (2019), 11852-11862. (DOI: 10.1021/acsomega.9b01629) [Selected as a front cover]
    6. Shogo Himori, Shoichi Nishitani and *T. Sakata “Effect of Electrochemically Grafted Aryl-Based Monolayer on Nonspecific Electrical Signal of Field-Effect-Transistor-Based Biosensor” ECS Trans., 89(6), (2019), 17-24. (DOI: 10.1149/08906.0017ecst)
    7. *T. Sakata “Biological sensing technology based on intrinsic molecular charges” Proceedings of SPIE, 11007, (2019), 1100703. (DOI: 10.1117/12.2518892)
    8. Akiko Saito and *T. Sakata “Sperm-Cultured Gate Ion-Sensitive Field-Effect Transistor for Nonoptical and Live Monitoring of Sperm Capacitation” Sensors, 19(8), (2019), 1784. (DOI: 10.3390/s19081784) [Selected as Editor’s Choice Article]
    9. Shogo Himori, Shoichi Nishitani and *T. Sakata “Control of Potential Response to Small Biomolecule with Electrochemically Grafted Aryl-Based Monolayer in Field-Effect-Transistor-Based Sensor” Langmuir, 35 (10), (2019), pp 3701–3709. (DOI: 10.1021/acs.langmuir.9b00085)
    10. Shoichi Nishitani and *T. Sakata “Polymeric Nanofilter Biointerface for Potentiometric Small-Biomolecule Recognition” ACS Appl. Mater. Interfaces, 11 (5), (2019), pp 5561–5569. (DOI: 10.1021/acsami.8b20010)

2018

  1. *Hayato Sone, Tomoyuki Kawakami, Akiko Saito, Yuki Sayama, Sumio Hosaka, and T. Sakata “Fabrication of Holder-type Piezoresistive Cantilever for Embryo Mass Measurement” Sensors and Materials, 30(10), (2018), 2369–2382. (DOI: 10.18494/SAM.2018.1951)
  2. *T. Sakata, Haruyo Sugimoto and Akiko Saito “Live monitoring of microenvironmental pH based on extracellular acidosis around cancer cells with cell-coupled gate ion-sensitive field-effect transistor” Analytical Chemistry, 90(21), (2018), 12731-12736. (DOI: 10.1021/acs.analchem.8b03070)
  3. Taira Kajisa and *T. Sakata “Molecularly Imprinted Artificial Biointerface for Enzyme-Free Glucose Transistor” ACS Appl. Mater. Interfaces,10(41), (2018), 34983–34990. (DOI: 10.1021/acsami.8b13317)
  4. Kensuke Ito, Kotaro Nishimura, Keiji Ikeda, Kazuya Matsuzawa, Tsutomu Tezuka and *T. Sakata “Charge-coupling extended-gate amorphous-InGaZnO-based thin-film transistor for use as ultrasensitive biosensor” Journal of The Electrochemical Society, 165, (2018), B571-B575. (DOI: 10.1149/2.0321813jes)
  5. *Taira Kajisa, Wei Li, Tsuyoshi Michinobu, *T. Sakata “Well-designed dopamine-imprinted polymer interface for selective and quantitative dopamine detection among catecholamines using a potentiometric biosensor” Biosensors and Bioelectronics, 117, (2018), 810-817. (DOI: 10.1016/j.bios.2018.07.014)
  6. Shoichi Nishitani, Yuki Maekawa and *T. Sakata “Understanding molecular structure of sialic acid/phenylboronic acid complex by a combined study of NMR and DFT: Point to note toward sialic acid detection at cell membrane” ChemistryOpen,7, (2018), 513–519. (DOI: 10.1002/open.201800071)
  7. *T. Sakata, Akiko Saito and Haruyo Sugimoto “In situ measurement of autophagy under nutrient starvation based on interfacial pH sensing” Sci. Rep., 8, (2018), 8282. (DOI: 10.1038/s41598-018-26719-4)
  8. Shoichi Nishitani and *T. Sakata “Three-Dimensional Polymeric Biointerface for Ultra-Sensitive and Selective Detection of Low-Molecular-Weight Biomarker Using Semiconductor-Based Biosensor” ECS Trans., 85(9), (2018), 9–14. (DOI: 10.1149/08509.0009ecst)
  9. Shoichi Nishitani and *T. Sakata “Potentiometric adsorption isotherm analysis of molecularly imprinted polymer interface for small-biomolecule recognition” ACS Omega, 3(5), (2018), pp 5382–5389. (DOI: 10.1021/acsomega.8b00627)
  10. Hiroto Satake, Akiko Saito and *T. Sakata “Elucidation of interfacial pH behaviour at cell/substrate nanogap for in situ monitoring of cellular respiration” Nanoscale, 10, (2018), 10130-10136. (DOI: 10.1039/C8NR02950D)
  11. Hiroto Satake and *T. Sakata “Electropolymerized Poly(toluidine blue O) Film Electrode for Potentiometric Biosensing” Sensors and Materials, 30(10), (2018), 2333–2341. (DOI: 10.18494/SAM.2018.1941)
  12. *B. M. Lowe, C-K. Skylaris, N. G. Green, Y. Shibuta and *T. Sakata “Molecular Dynamics Simulation of Potentiometric Sensor Response: Effect of Biomolecules, Surface Morphology and Surface Charge” Nanoscale, 10, (2018), 8650-8666. (DOI: 10.1039/C8NR00776D)
  13. *Toshiya Sakata and Akiko Saito “Review – Egg Cells on a Semiconductor: Potentials in Drug Screening and Clinical Diagnostics” ECS J. Solid State Sci. Technol., 7(7) (2018), Q3094-Q3103. (DOI: 10.1149/2.0121807jss)
  14. Haoyue Yang, Shoichi Nishitani, and *Toshiya Sakata “Potentiometric Langmuir isotherm analysis of histamine-selective molecularly imprinted polymer-based field-effect transistor” ECS J. Solid State Sci. Technol., 7(7) (2018), Q3079-Q3082. (DOI: 10.1149/2.0131807jss)
  15. Taira Kajisa, Yoshiyuki Yanagimoto, Akiko Saito, and *Toshiya Sakata “Biocompatible poly(catecholamine)-film electrode for potentiometric cell sensing” ACS sensors, 3 (2018) 476-483. (DOI:10.1021/acssensors.7b00897)
  16. Benjamin M. Lowe, Chirs-Kriton Skylaris, Nicolas G. Green, Yasushi Shibuta and *Toshiya Sakata “Calculation of surface potentials at the silica-water interface using molecular dynamics: Challenges and Opportunities” Japanese Journal of Applied Physics, 57 (2018) 04FM02. (DOI:10.7567/JJAP.57.04FM02)
  17. *Toshiya Sakata “[Review] In vitro diagnostic device with a bio-coupled gate field-effect transistor” International Journal of Automation Technology, 12 (2018) 45-51. (DOI:10.20965/ijat.2018.p0045)
  18. Taira Kajisa and *Toshiya Sakata Bioanalytical method based on extended-gate field-effect transistor modified by self-assembled monolayer” International Journal of Automation Technology, 12 (2018) 52-63. (DOI:10.20965/ijat.2018.p0052)

2017

  1. Haoyue Yang, Masatoshi Honda, Akiko Saito, Taira Kajisa, Yuhki Yanase and *Toshiya Sakata “Non-optical detection of allergic response with a cell-coupled gate field-effect transistor” Analytical Chemistry, 89 (2017) 12918-12923. (DOI:10.1021/acs.analchem.7b03688)
  2. Yuki Maekawa, Yasushi Shibuta and *Toshiya Sakata “Effect of ionic atmosphere around DNA/electrolyte interface on potentiometric signal” Journal of The Electrochemical Society, 164 (2017) B1-B5. (DOI:10.1149/2.0921712jes)
  3. Tsukuru Masuda, Taira Kajisa, Aya Mizutani Akimoto, Akane Fujita, Kenichi Nagase, Teruo Okano, *Toshiya Sakata and *Ryo Yoshida “Dynamic Electrical behaviour of thermoresponsive polymer in well-defined poly(N-isopropylacrylamide)-grafted semiconductor devices” RSC Advances, 7 (2017) 34517-34521. (DOI:10.1039/C7RA05786E)
  4. Yuta Uematsu, Taira Kajisa, and *Toshiya Sakata “Fundamental characteristics of glucose transistor with chemically functional interface” ChemElectroChem, 4 (2017) 1-8. (DOI:10.1002/celc.201700419)
  5. *Toshiya Sakata “Semiconductor-Based Biosensing Technology for Clinical Diagnosis” ECS Transactions, 77 (7) (2017) 3-9. (DOI:10.1149/07707.0003ecst)
  6. *Toshiya Sakata, Kotaro Nishimura, Yuuya Miyazawa, Akiko Saito, Hiroyuki Abe, Taira Kajisa “Ion sensitive transparent-gate transistor for visible cell sensing” Analytical Chemistry, 89 (2017) 3901-3908. (DOI:10.1021/acs.analchem.6b02246)
  7. Taira Kajisa, and *Toshiya Sakata “Development of paper-gate transistor toward direct detection from microbiological fluids” Japanese Journal of Applied Physics, 56 (2017) 04CM07. (DOI:10.7567/JJAP.56.04CM07)
  8. Hiroto Satake, Akiko Saito, Shuichi Mizuno, Taira Kajisa, and *Toshiya Sakata “Long-term and real-time monitoring of chondrocyte behavior synthesizing extracellular matrix with biologically coupled field effect transistor” Japanese Journal of Applied Physics, 56 (2017) 04CM03. (DOI:10.7567/JJAP.56.04CM03)
  9. Shoichi Nishitani, Taira Kajisa and *Toshiya Sakata “Development of molecularly imprinted polymer-based field effect transistor for sugar chain sensing” Japanese Journal of Applied Physics, 56 (2017) 04CM02. (DOI:10.7567/JJAP.56.04CM02)
  10. *Toshiya Sakata and Yusuke Matsuse In situ electrical monitoring of cancer cells invading vascular endothelial cells with semiconductor-based biosensor” Genes to Cells, 22 (2017), 203-209. (DOI:10.1111/gtc.12473)
  11. B. M. Lowe, Y. Maekawa, Y. Shibuta and *T. Sakata, C-K. Skylaris, *N. G. Green “Dynamic behaviour of the silica-water-bio electrical double layer in the presence of a divalent electrolyte” Physical Chemistry Chemical Physics, 19 (2017) 2687-2701. (DOI:10.1039/c6cp04101a)
  12. Taira Kajisa and *Toshiya Sakata “Glucose responsive hydrogel electrode for biocompatible glucose transistor” Sci. Technol. Adv. Mater., 18 (2017) 26-33. (DOI:10.1080/14686996.2016.1257344)


2016

  1. *Kazuhiro Sakamaki, Takahiro M. Ishii, Toshiya Sakata, Kiwamu Takemoto, Chiyo Takagi, Ayako Takeuchi, Ryo Morishita, Kumiko Chiba, Haruyo Sugimoto, Shuhei Tamate, Yutaka Satou, Satoshi Matsuoka, Koji Koyamada, Tatsuya Sawasaki, Takeharu Nagai and Naoto Ueno, “Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage” BBA – Molecular Cell Research, 1863 (2016) 2766-2783. (DOI:10.1016/j.bbamcr.2016.08.010)
  2. Taira Kajisa, and *Toshiya Sakata “Monitoring of hydroxyapatite crystal formation using field-effect transistor” Japanese Journal of Applied Physics, 55 (2016) 04EM09. (DOI:10.7567/JJAP.55.04EM09)
  3. T. Izak, V. Prochazka, T. Sakata, B. Rezek, and *A. Kromka “Real-time monitoring of cell activities by diamond solution-gated field effect transistors” Procedia Engineering, 158 (2016) 469-472. (DOI:10.1016/j.proeng.2016.11.130)

2015

  1. Taira Kajisa, and *Toshiya Sakata “Characterization of ion-sensitive extended-gate field effect transistor coated with functional self-assembled monolayer” Japanese Journal of Applied Physics, 54 (2015) 04DL06. (DOI:10.7567/JJAP.54.04DL06)
  2. T. Izak, T. Sakata, Y. Miyazawa, T. Kajisa, A. Kromka, *B. Rezek “Diamond-coated field-effect sensor for DNA recognition – Influence of material and morphology” Diamond and Related Materials, 60 (2015) 87-93. (DOI:10.1016/j.diamond.2015.10.020)
  3. Hirokazu Nishida, Taira Kajisa, Yuuya Miyazawa, Yuki Tabuse, Takuya Yoda, Haruko Takeyama, Hideki Kambara, and *Toshiya Sakata “Self-oriented immobilization of DNA polymerase tagged by titanium-binding peptide motif” Langmuir, 31 (2015) 732-740. (DOI:10.1021/la503094k)
  4. Yuki Maekawa, Yasushi Shibuta, and *Toshiya Sakata “Effect of double-stranded DNA on electrical double layer structure at oxide/electrolyte interface in classical molecular dynamics simulation” Chem. Phys. Lett., 619 (2015) 152-157. (DOI:10.1016/j.cplett.2014.11.068)

2014

  1. Taira Kajisa and *Toshiya Sakata “Fundamental property of phenylboronic-acid-coated gate field-effect transistor for saccharide sensing” ChemElectroChem, 1 (2014) 1516-1524. (DOI: 10.1002/celc.201402193)
  2. 前川 侑毅, 澁田 靖, *坂田 利弥 “大規模分子動力学法による半導体/バイオインターフェイス構造の解明” 表面技術 65(6) (2014) 251-256.
  3. Haruyo Sugimoto and *Toshiya Sakata “Cell adhesion monitoring of human induced pluripotent stem cell based on intrinsic molecular charges” Japanese Journal of Applied Physics. 53 05FS02(2014). (DOI:10.7567/JJAP.53.05FS02)
  4. Yuuya Miyazawa and *Toshiya Sakata “Molecular charge contact biosensing based on the interaction of biologically modified magnetic beads with an ion-sensitive field effect transistor” European Biophysics Journal, 43 (2014) 217-225. (DOI: 10.1007/s00249-014-0948-y)
  5. Yuki Maekawa, Yasushi Shibuta, and *Toshiya Sakata “Distinctive potential behavior at oxidized surface of semiconductor device in concentrated aqueous salt solution” ChemElectroChem, 1 (2014) 1647-1655. (DOI:10.1002/celc.201402069)
  6. Hirokazu Nishida, Kiyofumi Takahashi, Yuki Tabuse, Hideki Kambara,and *Toshiya Sakata “Real-time monitoring of voltage shift based on enzymatically-released pyrophosphate using phenylboronic acid-immobilized gate field effect transistor” Japanese Journal of Applied Physics. 53 04EL04(2014). (DOI:10.7567/JJAP.53.04EL04)

2013

  1. *Toshiya Sakata, Akiko Saito, Jinji Mizuno, Haruyo Sugimoto, Kaori Noguchi, Eiko Kikuchi, Hiroaki Inui “Single embryo-coupled gate field effect transistor for elective single embryo transfer” Analytical Chemistry,85 (14)(2013),6633-6638. (DOI:10.1021/ac4001018)
  2. *Toshiya Sakata, Ryushi Fukuda “Simultaneous biosensing with quartz crystal microbalance with dissipation coupled-gate semiconductor device” Analytical Chemistry, 85 (12) (2013), 5796–5800. (DOI:10.1021/ac400468m)
  3. Yuki Maekawa, Yasushi Shibuta, and *Toshiya Sakata “Charge Behaviors around Oxide Device/Pseudo-Physiological Solution Interface with Molecular Dynamic Simulations” Japanese Journal of Applied Physics,52 (14)(2013). (DOI: 10.7567/JJAP.52.127001)
  4. *Hidenori Otsuka, Masako Nagamura, Akie Kaneko, Koichi Kutsuzawa and Toshiya Sakata “Label-Free and Noninvasive Monitoring of Cell Differentiation on Spheroid Microarray” IEICE Transactions on Electronics E96.C(3) (2013) 353-357. (DOI: 10.1587/transele.E96.C.353)

2012

  1. *Toshiya Sakata, Izumi Makino, Haruyo Sugimoto “Real-time monitoring of potassium ion release due to apoptosis with cell-based transparent-gate transistor” Applied Physics Express, 5(2012). (DOI: 10.1143/APEX.5.017001)
  2. *Hidenori Otsuka, Masako Nagamura, Akie Kaneko, Koichi Kutsuzawa,Toshiya Sakata and Yuji Miyahara “Chondrocyte spheroids on microfabricated PEG hydrogel surface and their noninvasive functional monitoring” Science and Technology of Advanced Materials, 13 (2012), 1-8. (DOI: 10.1088/1468-6996/13/6/064217)

2011

  1. 坂田 利弥,水野仁二,杉本東代,喜多清,野口香里,菊池瑛子,乾 裕昭 “半導体バイオセンシング技術による胚クオリティーの評価” 日本受精着床学会雑誌,28(2011).329-334.
  2. *Toshiya Sakata and Haruyo Sugimoto “Continuous Monitoring of Electrical Activity of Pancreatic β-Cells Using Cell-Based Field Effect Transistor” Japanese Journal of Applied Physics,50(2011), (DOI: 10.1143/JJAP.50.020216)
  3. *Toshiya Sakata, Izumi Makino and Sayaka Kita “Real-time and noninvasive monitoring of sea urchin embryo activity using semiconductor devices” European Biophysics Journal, 40 (2011),699-704. (DOI: 10.1007/s00249-010-0653-4)

2010

  1. Taiichiro Murakami, *Toshiya Sakata, Akira Matsumoto, Madoka Takai, Kazuhiko Ishihara, Yuji Miyahara “Development of cell/transistor interface for real-time and noninvasive monitoring of potassium ion release based on apoptosis using biologically-coupled field effect transistor” Transactions of the Materials Research Society of Japan, 35 (2010), 255-258. (DOI:10.14723/tmrsj.35.255)

2009

  1. Akira Matsumoto, Naoko Sato, *Toshiya Sakata, Kazunori Kataoka and Yuji Miyahara “Chemical-to-Electrical-Signal Transduction Synchronized with Smart Gel Volume Phase Transition” Advanced Materials, 21 (2009), 4372-4378. (DOI: 10.1002/adma.200900693)
  2. Masaki Ihara, Toshiya Sakata, Izumi Makino, Yuji Miyahara and Hiroshi Ueda “Open sandwich-based immuno-transistor for label-free and highly sensitive detection of low molecular weight antigens” Journal of Bioscience and Bioengineering 108 (2009). (DOI:10.1016/j.jbiosc.2009.08.426)
  3. *Toshiya Sakata,Masaki Ihara,Izumi Makino, Hiroshi Ueda and Yuji Miyahara “Open sandwich-based immuno-transistor for label-free and highly sensitive detection of low molecular weight antigen” Analytical Chemistry, 81(2009), 7532-7537. (DOI: 10.1021 /ac900457m)
  4. *Toshiya Sakata and Yuji Miyahara “Charged-Nanosphere-Coupled Biotransistor for Highly Sensitive Genetic Analysis” Current Applied Physics, 9 (2009), e210-e213. (DOI: 10.1016/j.cap.2009.05.034)
  5. Akira Matsumoto, Naoko Sato, Toshiya Sakata, Kazunori Kataoka and Yuji Miyahara “Glucose-sensitive field effect transisto using totally synthetic compounds” The Journal of Solid State Electrochemistry, 13 (2009), 165-170. (DOI: 10.1007/s10008-008-0610-7)
  6. Toshiya Sakata and Yuji Miyahara “Capacitance-Voltage Measurement of Transporting Function at Cell Membrane” IEEJ Transactions on Sensors and Micromachines, 129 (2009), 242-244. (DOI: 10.1541/ieejsmas.129.242)

2008

  1. *Toshiya Sakata, Izumi Makino, Sayaka Kita and Yuji Miyahara “Electrical Detection Ovum Membrane Charges Using Biotransistor” Microelectronics Engineering, 85 (2008), 1337-1340. (DOI: 10.1016/j.mee.2008.01.030)
  2. Toshiya Sakata and *Yuji Miyahara “Non-invasive monitoring of transporter-substrate interaction at cell membrane” Analytical Chemistry, 80 (2008), 1493-1496. (DOI: 10.1021/ac701977e)
  3. Toshiya Sakata and *Yuji Miyahara “Detection of molecular charges at cell membrane” Japanese Journal of Applied Physics, 47 (2008), 368-370. (DOI: 10.1143/JJAP.47.368)

2007

  1. Toshiya Sakata, Aiko Ueda and *Yuji Miyahara “Cell adhesion characteristics to chemically modified silicon nitride surface” IEEJ Transactions on Electrical and Electronic Engineering, 2 (2007), 295-300. (DOI: 10.1002/tee.20153)
  2. *Yukichi Umakoshi, Hiroyuki Yasuda and Toshiya Sakata “Control of texture in intermetallic compounds by thermomechanical processing” Solid State Phenomena, 127 (2007), 9-13. (DOI: 10.4028/www.scientific.net/SSP.127.9)
  3. Toshiya Sakata, Sumio Maruyama, Aiko Ueda, Hidenori Otsuka and Yuji Miyahara “Stable immobilization of an oligonucleotide probe on a gold substrate using tripodal thiol-derivatives” Langmuir, 23 (2007), 2269-2272. (DOI: 10.1021/la0616193)
  4. Toshiya Sakata and *Yuji Miyahara “Direct transduction of allele-specific primer extension into electrical signal using genetic field effect transistor” Biosensors and Bioelectronics, 22 (2007) 1311-1316. (DOI: 10.1016/j.bios.2006.05.031)

1999-2006

  1. Toshiya Sakata and *Yuji Miyahara “DNA sequencing based on intrinsic molecular charges Angewandte Chemie International Edition, 45 (2006), 2225-2228. (DOI: 10.1002/anie.200503154)
  2. Toshiya Sakata and *Yuji Miyahara “Detection of DNA recognition events using multi-well field effect transistor” Biosensors and Bioelectronics, 21 (2005), 827-832. (DOI: 10.1016/j.bios.2005.01.018)
  3. Toshiya Sakata, Shinya Matsumoto, Yoshio Nakajima and *Yuji Miyahara “Potential Behavior of Bio-chemically Modified Gold Electrode for Extended Gate Field Effect Transistor” Japanese Journal of Applied Physics, 44 No. 4B (2005), 2860-2863. (DOI: 10.1143/JJAP.44.2860)
  4. Toshiya Sakata, Masao Kamahori and *Yuji Miyahara “DNA Analysis Chip Based on Field Effect Transistors” Japanese Journal of Applied Physics, 44 No. 4B (2005), 2854-2859. (DOI: 10.1143/JJAP.44.2854)
  5. Toshiya Sakata and *Yuji Miyahara “Potentiometric detection of single nucleotide polymorphism using genetic field effect transistor” ChemBioChem, 6 (2005), 703-710. (DOI: 10.1002/cbic.200400253)
  6. Toshiya Sakata, Masao Kamahori and *Yuji Miyahara “Immobilization of oligonucleotide probes on Si3N4 surface and its application to genetic field effect transistor” Mat. Sci. Eng. C, 24 (2004), 827-832. (DOI: 10.1016/j.msec.2004.08.042)
  7. Toshiya Sakata, Hiroyuki Yasuda and *Yukichi Umakoshi “Effect of coherency on interphase boundary sliding in NiAl(β) bicrystals with film-like Ni3Al(γ’) precipitate along boundary” Scripta Mater., 48(2003), 749-753. (DOI: 10.1016/S1359-6462(02)00538-9)
  8. Toshiya Sakata, Hiroyuki Yasuda and *Yukichi Umakoshi “Interphase boundary fracture and grain boundary precipitation of Ni3Al(γ’) phase in β-NiAl bicrystals” Acta Mater., 51 (2003), 1561-1572. (DOI: 10.1016/S1359-6454(02)00558-X)
  9. Toshiya Sakata, H. Kohma, Hiroyuki Yasuda and *Yukichi Umakoshi “Texture development during dynamic recrystallisation in hot-deformed Fe-40at.%Al alloy” ISIJ International, 42 (2002), 903-909. (DOI: 10.2355/isijinternational.42.903)
  10. Toshiya Sakata, Hiroyuki Yasuda and *Yukichi Umakoshi “Concurrent design for NiAl-based(β/γ’) two-phase alloys by controlling microstructure and texture” Science and Technology of Advanced Materials,3(2002),157-164. (DOI:10.1016/S1468-6996 (02) 00006-2)
  11. Toshiya Sakata, Hiroyuki Yasuda and *Yukichi Umakoshi “Formation of deformation bands and precipitation of Ni3Al(γ’) phase in NiAl(β)-based single crystals by thermomechanical processing” Intermetallics, 10(2002), 139-147. (DOI:10.1016/S0966-9795(01)00112-1)
  12. Toshiya Sakata, Hiroyuki Yasuda and *Yukichi Umakoshi “Development of microstructure and texture in rapidly solidified and annealed Ni-Al alloys” Mater. Trans. JIM, 42 (2001), 2382-2385. (ISSN: 1347-5320)
  13. Toshiya Sakata, Hiroyuki Yasuda and *Yukichi Umakoshi “Control of microstructure and orientation distribution in Ni-Al-based (β/γ’) two phase alloys by thermomachanical processing” Acta Mater., 49(2001),4231-4239. (DOI: 10.1016/S1359-6454(01)00310-X)
  14. Toshiya Sakata, Hiroyuki Yasuda and *Yukichi Umakoshi “Formation process of transformation texture from the β to α phase in Cu-42mass%Zn alloy” Scripta Mater., 43 (2000), 411-416. (DOI: 10.1016/S1359-6462(00)00438-3)
  15. Hiroyuki Yasuda, Toshiya Sakata and *Yukichi Umakoshi “Variant selection in transformation texture from the β to α phase in Cu-40mass%Zn alloy” Acta Mater., 47 (1999), 1923-1933. (DOI: 10.1016/S1359-6454(99)00038-5)

Reviews and Handbooks

  1. Toshiya Sakata, “Point of Care Diagnostics on a Chip”: Springer (edited by Robert M Westervelt and David Issadore), “Chapter 6. Semiconductor-based biosensing chip for point-of-care diagnosis” (2013), 125-152.
  2. 坂田 利弥, “半導体バイオセンシング技術による胚の評価法”, 「産と婦人科 別冊」, 78 (2011),952-958.
  3. 坂田 利弥, “半導体バイオセンシング技術による胚クオリティーの評価”, 日本受精着床学会雑誌, 28 (2011),329-334.
  4. 坂田 利弥, “バイオ/半導体シグナル変換界面におけるセラミックス薄膜の役割と生体機能計測”,セラミック機能化ハンドブック,(2011), 419-424.
  5. Biosensing Devices: Science and Application edited by Toshiya Sakata, (Pan Stanford Publishing), in preparation (2009-2010).
  6. 宮原 裕二, 坂田 利弥, 松元 亮, 片岡 知歩, “バイオトランジスタによる生体分子認識の検出”, 「バイオチップ 実用化ハンドブック」(NTS出版), (2010), 518-528.
  7. Yuji Miyahara, Toshiya Sakata and Akira Matsumoto, ”Microbial Genetic Analysis Based on Field Effect Transistors” in Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems, Springer Science, in press (2008).
  8. 坂田 利弥, 松元 亮, 宮原 裕二, “電界効果を基本原理としたバイオセンシングデバイス”, マテリアルインテグレーション, 20 (2007), 50-56.
  9. 坂田 利弥, 松元 亮、宮原 裕二, “遺伝子解析用バイオトランジスタ”, 機能性材料, 27 (2007), 25-34.
  10. 坂田 利弥, 宮原 裕二, “バイオトランジスタによる生体分子認識の電気的検出”, 応用物理, 74 (2005), 1555-1562.
  11. 宮原 裕二, 坂田 利弥, “電界効果トランジスタを用いた遺伝子解析チップ”, ケミカルエンジニアリング, 50 (2005), 508-514.
  12. 宮原 裕二, 丸山 純夫, 坂田 利弥, “バイオナノエレクトロニクス”, ナノマテリアルズハンドブック(NTS出版), (2005), 745-749.
  13. 坂田 利弥, 宮原 裕二, “MEMS技術のバイオチップへの応用”, バイオサイエンスとインダストリー , 62 (2004), 577-582.
  14. 宮原 裕二, 坂田 利弥, “マイクロマシンのバイオチップ応用”, 静電気学会誌, 27 (2003), 268-272.

Invited lectures

  1. 坂田利弥, “エレクトロバイオが開く医学・創薬研究”,薬理学会年会プレセミナー, weworkオーシャンゲートみなとみらい, 2020/02/19.
  2. Toshiya Sakata, ” Biologically coupled gate field-effect transistors meet in vitro diagnostics”, IEEE-NANOMED 2019, Gwangju, Korea, 2019/11/22.
  3. 坂田利弥, “半導体バイオセンサの原理と体外診断への可能性”, LG Japan Lab (株)セミナー, LG Japan Lab (株), 2019/10/03.
  4. Toshiya Sakata, ” Biological sensing technology based on intrinsic molecular charges”, SPIE. DEFENSE+COMMERCIAL SENSING 2019, Baltimore, Ml, US, 2019/04/14.
  5. 坂田利弥, “診断医療における半導体バイオセンサの可能性”, 電気化学会 第85回大会, 東京理科大学葛飾キャンパス, 2018/06/03.
  6. 坂田利弥, “診断医療における半導体バイオセンサの可能性”, 第117回日本皮膚科学会, リーガロイヤルホテル広島, 2018/03/09.
  7. Toshiya Sakata, ” Semiconductor-Based Biosensing Technology for Clinical Diagnosis”, AM-FPD 2017, Kyoto, Japan, 2017/07/06.
  8. Toshiya Sakata, ” Semiconductor-Based Biosensing Technology for Clinical Diagnosis”, 231st ECS Meeting 2017, New Orleans, US, 2017/05/28-06/01.
  9. 坂田利弥, “半導体バイオセンサの現状と展望”, 第20回 名古屋大学VBLシンポジウム, 名古屋大学フロンティアプラザ, 2016/11/29.
  10. Toshiya Sakata, “In Vitro Bio-Circuit Sensing Based on Cell-Semiconductor Interaction”, ICSJ 2015, Kyoto, Japan, 2015/11/10.
  11. Toshiya Sakata, “Semiconductor-Based Biosensing Technology for Clinical Diagnosis”, 6th MSF 2015, Washinton, DC, US, 2015/11/06.
  12. 坂田利弥, “細胞診断に向けた半導体バイオセンシング技術”, 第28回 日本動物細胞工学会2015年度大会 (JAACT2015), 東北大学 片平さくら ホール, 2015/07/10.
  13. Toshiya Sakata, “Semiconductor-Based Biosensing Technology for Clinical Diagnosis”, 2015 Symposium on VLSI Technology, Kyoto, Japan, 2015/06/15.
  14. Toshiya Sakata, “Semiconductor-Based Biosensing Technology for Clinical Diagnosis”, ISNE 2016, Hsinchu, Taiwan, 2016/05/06.
  15. Toshiya Sakata, “Semiconductor-based biosensing platform for clinical diagnosis”, International Forum on Smart Bio-semiconductor Technology & Standard, Seoul, 2014/3/27.
  16. 坂田 利弥, “診断医療・バイオ分野に向けたin vitroバイオサーキットセンシング技術”, 有機分子バイオエレクトロニクス分科会3月研究会, 東京大学山上会館, 2014/3/5.
  17. 坂田 利弥, “胚の客観的評価に向けた半導体バイオセンシング技術”, 牛繁殖技術と工学技術の融合についてシンポジウム, 独立行政法人 家畜改良センター講堂, 2014/2/26.
  18. Toshiya Sakata, “In vitro Bio-circuit Sensing with Integrated Bio/Semiconductor Platform”, AMDE2013, 桐生市民文化会館, 2013/12/19.
  19. 坂田利弥, “「半導体原理を融合したQCM-Dの新展開」細胞・生体分子のイオン変化をQCM-D同時測定 ”,QCM-Dセミナー,東京八重洲ホール, 2013/11/19.
  20. 坂田利弥, “バイオ・医療分野における半導体バイオセンサの可能性”,山形大学有機エレクトロニクス研究センター, 2013/10/17.
  21. 坂田利弥, “診断医療・創薬分野における半導体バイオセンシング技術の可能性”,日本化薬株式会社, 2013/10/3.
  22. Toshiya Sakata, “In vitro Bio-circuit Sensing with Integrated Bio/Semiconductor Platform”,JSAP-MRSジョイントシンポジウム,同志社大学,2013/9/17.
  23. 坂田利弥, “バイオ・医療分野における半導体バイオセンシング技術の方向性”,応用物理学会 有機分子バイオ分科会, 豊田中央研究所 アクタスAホール, 2013/8/21.
  24. 坂田利弥, “バイオ・医療分野における半導体バイオセンシング技術”,株式会社 日立製作所 中央研究所, 2013/7/25.
  25. Toshiya Sakata, “Semiconductor-based biosensing technology”,Academy of Sciences of the Czech Republic, 2012/11/6.
  26. Toshiya Sakata, “Semiconductor-based biosensing technology”,Forschungszentrum Jülich,2012/10/31.
  27. 坂田利弥, “診断医療・創薬・環境モニタリングに向けた半導体バイオセンシングプラットフォーム”,精密工学会 超精密加工専門委員会 第64回研究会,メルパルク大阪, 2012/10/4.
  28. Toshiya Sakata, “In vitro cell sensing with semiconductor-based biosensing technology”,IUMRS-ICEM,NTT武蔵野研究開発センター, 2012/6/8.
  29. Toshiya Sakata, “半導体バイオセンシング技術を組み合わせたQCM-Dの新たな可能性”,QCM-Dアプリケーションセミナー(メイワフォーシス) ,タワーホール船堀, 2011/12/14.
  30. Toshiya Sakata, “Cell Sensing with Bio-coupled Gate Semiconductor”,15th International Conference on Thin Films ,Kyoto Terrsa, 2011/11/11.
  31. Toshiya Sakata, “Biological-switch-gate semiconductor-based biosensing”, ISOEN2011,Rockefeller University, 2011/5/3.
  32. 坂田利弥, “生体機能がスイッチ制御する半導体バイオセンシング技術”, 日本学術振興会142研究会,東京理科大学, 2011/03/10.
  33. 坂田利弥, “生体機能がスイッチ制御する半導体バイオセンシング技術”, バイオセンサ・医療デバイス 応用物理, 2010/12/13.
  34. 坂田利弥, “半導体原理に基づくラベルフリーDNAシーケンシング実現のためのバイオインターフェース制御”, JST 技術説明会, 2010/11/11.
  35. 坂田利弥, “医療・創薬応用を目指した半導体バイオセンシング技術”, 次世代マイクロ化学チップコンソーシアム, 東京大学, 2010/10/28.
  36. 坂田利弥, “半導体バイオセンシング技術と生体機能計測”, NanoBioセミナー, 東京大学理学部, 2010/7/8.
  37. 坂田利弥, “半導体バイオセンシング技術と生体機能計測”, 第6回バイオナノエレクトロニクス学術講演会, 東海大学, 2010/4/23.
  38. 坂田利弥, “半導体バイオセンシング技術とAFMの利用”, Agilnent seminar, 2010/4/20.
  39. 坂田利弥, “半導体バイオセンシング技術と生体機能計測”, 応用物理学会シンポジウム, 2010/3/18.
  40. 坂田利弥, “半導体バイオセンシング技術と生体機能計測”, 日本学術振興会, 2010/3/5.
  41. 坂田 利弥,“半導体バイオセンシング技術と生体機能計測”, インテリジェントナノプロセス, 東北大学, 2009/12/18.
  42. 坂田 利弥, “バイオ/半導体シングナル変換界面の創製と生体機能計測”, コロイドおよび界面化学討論会, 2009/9/17.
  43. 坂田 利弥, “生殖補充医療を指向したバイオセンシング技術の検討”, A-PART, 2009/5/30.
  44. Toshiya Sakata, “Field effect-based biosensing devices for bio-functional analysis”, the Indo-Japan Workshop on Nanobiotechnology & Nanodevices (SASTRA University in Thanjavur, India), 2009/1/23-24.
  45. 坂田利弥, 宮原裕二, “バイオトランジスタによる生体分子機能解析”, 応用物理学会, 2008/3/28.
  46. Toshiya Sakata, “Cell-based Field Effect Devices for Cell Functional Analysis”, Micro and Nano Engineering (MNE) 2007 (Copenhagen), 2007/9/24.
  47. 坂田利弥, 宮原裕二, “バイオトランジスタによる生体分子認識の電気的検出”, 電気学会, 2006/1/27.
  48. 坂田利弥, 宮原裕二, “Cell Functional Analysis Using Field Effect Devices”, 第22回「センサ・マイクロマシンと応用システム」シンポジウム 電気学会, 2005/10/20-2005/10/21.
  49. 坂田利弥, 宮原裕二, “遺伝子トランジスタを用いたDNAシークエンシングの検討”, 電気学会, 2005/9/22.

General presentations

  1. Shoichi Nishitani, Toshiya Sakata, “Polymeric nanofilter-based biointerface for potentiometric small-biomolecule recognition”, MRS 2019, Boston, MA, US, 2019/12/04.
  2. Shoichi Nishitani, Toshiya Sakata, “Polymeric nanofilter biointerface for potentiometric small-biomolecule recognition”, ACS Fall 2019 National Meeting & Exposition, San Diego, CA, US, 2019/08/28.
  3. Akane Fujita, Tsukuru Masuda, Aya Akimoto, Taira Kajisa, Ryo Yoshida, Toshiya Sakata, “Stimuli-Responsive Polymer-Grafted Gate Field-Effect Transistor for Bioanalytical Sensor”, MRS 2018, Boston, WA, US, 2018/11/29.
  4. Shogo Himori, Shoichi Nishitani, Toshiya Sakata, “Artificially Well-Designed Biomonolayer for Prevention of Nonspecific Electrical Signal”, MRS 2018, Boston, WA, US, 2018/11/28.
  5. Shoichi Nishitani, Toshiya Sakata, “Three-dimensional polyfilter interface for sensitive and selective detection of low-molecular-weight biomarker using potentiometric biosensor”, 256th ACS National Meeting & Exposition, Boston, MA, US, 2018/08/19.
  6. Hiroto Satake, Akiko Saito, Toshiya Sakata, “In situ monitoring of cellular respiration with interfacial pH detection at cell/substrate nanogap”, BIOSENSORS 2018, Miami, Fl, US, 2018/06/12-15.
  7. Shoichi Nishitani, Toshiya Sakata, “Three-Dimensional Polymeric Biointerface for Ultra-Sensitive and Selective Detection of Low-Molecular-Weight Biomarker Using Semiconductor-Based Biosensor”, 233rd ECS Meeting 2018, Seattle, WA, US, 2018/05/14.
  8. B. M. Lowe, Y. Maekawa, C. -K. Skylaris, N. Green, Y. Shibuta, Toshiya Sakata, “Molecular Dynamics Investigation of the Field-Effect at the Technologically Relevant Silica-Electrolyte Interface”, SSDM 2017, Sendai, Japan, 2017/09/21.
  9. Shoichi Nishitani, Toshiya Sakata, “Surface Modification with Aryldiazonium Salt Chemistry of Extended-Au Gate Field-Effect Transistor for UltraSensitive Detection of Low-Molecular-Weight Biomarker”, SSDM 2017, Sendai, Japan, 2017/09/21.
  10. Kensuke Ito, Kotaro Nishimura, K. Ikeda, K. Matsuzawa, T. Tezuka, Toshiya Sakata, “Ultra-sensitive biosensor with capacitive coupling-gate InGaZnO-based FET”, SSDM 2017, Sendai, Japan, 2017/09/21.
  11. Toshiya Sakata, “Solution-gate semiconductor-based biosensor”, SISPAD 2017, Kamakura, Japan, 2017/09/06.
  12. Shoichi Nishitani, Toshiya Sakata, “Towards selective molecular biosensing: Fundamental investigation of polymeric filtering effect on field-effect transistor biosensor”, ACS 254th National Meeting 2017, Washington, DC, US, 2017/08/20.
  13. Haoyue Yang, Akiko Saito, Taira Kajisa, Yuki Yanase, Toshiya Sakata, “Development of a Novel Device for Allergy Test Based on Semiconductor Principle”, MRS 2016, Boston, WA, US, 2016/11/27-12/02.
  14. Shoichi Nishitani, Taira Kajisa, Toshiya Sakata, “Development of Molecularly Imprinted Polymer-Gate Field Effect Transistor for Sugar Chain Sensing”, MRS 2016, Boston, MA, US, 2016/11/27-12/02.
  15. Taira Kajisa, Toshiya Sakata, “Development of Paper-based Transistor Toward Direct Detection from Micro Biological Fluids”, SSDM 2016, Tsukuba, Japan, 2016/09/27.
  16. Hiroto Satake, Akiko Saito, Taira Kajisa, S. Mizuno, Toshiya Sakata, “Long-term and Real-time Monitoring of Chondrocytes Behavior Synthesizing Extracellular Matrix with Biologically-coupled Field Effect Transistor”, SSDM 2016, Tsukuba, Japan, 2016/09/27.
  17. Shoichi Nishitani, Taira Kajisa, Toshiya Sakata, “Development of Molecularly Imprinted Polymer-Gate Field Effect Transistor for Sugar Chain Sensing”, SSDM 2016, Tsukuba, Japan, 2016/09/27.
  18. Haoyue Yang, Akiko Saito, Taira Kajisa, Yuki Yanase, Toshiya Sakata, “Development of a Novel Device for Allergy Test Based on Semiconductor Principle”, MRS 2015, Boston, WA, US, 2015/11/29-12/04.
  19. Taira Kajisa, Toshiya Sakata, “Monitoring of Hydroxyapatite Crystal Formation using Field Effect Transistor”, SSDM 2015, Sapporo, Japan, 2015/09/30.
  20. Hiroto Satake, Akiko Saito, Taira Kajisa, S. Mizuno, Toshiya Sakata, “In situ Monitoring of Extracellular Matrix Based on Chondrocytes Behavior using Biologically-coupled Field Effect Transistor”, SSDM 2015, Sapporo, Japan, 2015/09/29.
  21. Haoyue Yang, Akiko Saito, Taira Kajisa, Yuki Yanase, Toshiya Sakata, “Development of a Novel Device for Allergy Test Based on Semiconductor Principle”, SSDM 2015, Sapporo, Japan, 2015/09/29.
  22. Taira Kajisa and Toshiya Sakata, “Characterization of ion sensitive extended-gate field effect transistor coated by functional self-assembled monolayer”, SSDM 2014, Tsukuba, Japan, 2014/09/10.
  23. Yuki Maekawa, Y. Shibuta and Toshiya Sakata, “Elucidation of semiconductor / biointerface structure by molecular dynamics simulation”, SSDM 2014, Tsukuba, Japan, 2014/09/10.
  24. Toshiya Sakata, “Simultaneous bio-parameter sensing with QCM-D coupled-gate semiconductor device”, BIOSENSORS 2014, Melbourne, Australia, 2014/05/30.
  25. Toshiya Sakata, “Single mouse embryo-coupled gate semiconductor for elective single embryo transfer”, BIOSENSORS 2014, Melbourne, Australia, 2014/05/29.
  26. Masatoshi Honda, Akiko Saito, Taira Kajisa, Yuhki Yanase, Toshiya Sakata, “Semiconductor-Based Bio-Sensing for Allergy Tests”,MRS2013, Boston.,2013/12/4.
  27. Yuta Uematsu, Taira Kajisa, Toshiya Sakata, “Fundamental Properties on Glucose Transistor for Noninvasive Glucose Sensing”,MRS2013, Boston.,2013/12/3.
  28. Taira Kajisa, Yuta Uematsu, Toshiya Sakata, “Development of Saccharide-Based Date Field Effect Transistor for Various Biosensing Applications”,MRS2013, Boston.,2013/12/3.
  29. Toshiya Sakata, “In vitro Bio-circuit Sensing with Integrated Bio/Semiconductor Platform”,AMDE2013, Kiryu,Gunma, 2013/11/29.
  30. H. Nishida, K. Takahashi, Y. Tabuse, A. Matsumoto,Y. Miyahara, H. Kambara and Toshiya Sakata, “Direct observation of the enzymatically-released pyrophosphates using phenylboronic acid group-immobilized gold electrode by FET”, SSDM2013,Fukuoka, 2013/9/26.
  31. Toshiya Sakata, “ Novel evaluation system of single embryo quality based on semiconductor technology”, ISIVF2013, Tunis, 2013/9/5.
  32. Toshiya Sakata, “In Vitro Bio-Circuit Sensing with Integrated Bio/Semiconductor Platform”, Osaka, Japan, IEEE EMBC’13, 2013/7/5.
  33. Toshiya Sakata, “ In vitro cell sensing with semiconductor-based biosensing technology”, BIOSENSORS 2012,Cancun,Mexico,2012/05/16.
  34. Toshiya Sakata, “ Semiconductor-based biosensing for life science”, secondBio-Sensing Technology, Amsterdam, 2011/10/11.
  35. Toshiya Sakata,“Cell/Semiconductor Signal Transduction Interface for Cell Death Detection”,MRS2010, Boston, 2010/11/30.
  36. Toshiya Sakata,“Biologically-switchable Gate Semiconductor for Bio-functional Analysis”,MRS2010, Boston, 2010/11/30.
  37. Toshiya Sakata,“Semiconductor-Based Biosensing Technology for Bio-Functional Analysis and High-Throughput Drug Screening”, 5th Annual Assay & Drug Discovery Technologies, San Diego, 2010/09/20.
  38. Toshiya Sakata, Taichiro Murakami and Haruyo Sugimoto, “Real-time and label-free monitoring of apoptosis using semiconductor-based biosensing device”, BIOSENSORS 2010, Glasgow, UK, 2010/5/26.
  39. Toshiya Sakata, “Real-time cell sensing on multi functional semiconductor”, 6th Assay&Drug Discovery Technologies, San Francisco, 2011/7/8.
  40. Toshiya Sakata, Taichiro Murakami and Haruyo Sugimoto, “Real-time and label-free monitoring of apoptosis using semiconductor-based biosensing device”, BIOSENSORS 2010, Glasgow, UK, 2010/5/26.
  41. Yusuke Matsuse, Takanori Kihara, Toshiya Sakata and Yuji Miyahara, “Noninvasive real-time monitoring of invasion process of tumor cells using vascular endothelial cell-based transistor”, BIOSENSORS 2010, Glasgow, UK., 2010/5/26
  42. Toshiya Sakata and Sayaka Kita, “Semiconductor-based biosensing device for assisted reproductive technology”, BIOSENSORS 2010, Glasgow, UK, 2010/5/26.
  43. Toshiya Sakata and Sayaka Kita, “Real-time and noninvasive monitoring of embryo activity using semiconductor devices”, First Bio-Sensing Technology Conference, Bristol, UK, 2009/11/10-12.
  44. Toshiya Sakata, Masaki Ihara, Izumi Makino, Yuji Miyahara and Hiroshi Ueda, “Open sandwich-based immuno-transistor for label-free and highly sensitive detection of low molecular weight antigen”, ACS2009, 2009/8/16.
  45. Toshiya Sakata and Sayaka Kita, “Real-time and noninvasive monitoring of embryo activity using semiconductor devices”, NanoBio Europe 2009, 2009/6/17.
  46. Toshiya Sakata, “Field effect-based biosensing devices for bio-functional analysis”, the Indo-Japan Workshop on Nanobiotechnology & Nanodevices (SASTRA University in Thanjavur, India), 2009/1/23-24.
  47. Akira Matsumoto, Naoko Sato, Toshiya Sakata, Kazunori Kataoka and Yuji Miyahara, “Non-invasive and Quantitative Monitoring of Cell Membrane Carbohydrates using Phenylboronic Acid Gate Modified Field Effect Transistor”, MRS2008, 2008/12/2.
  48. Koji Futamura, Toshiya Sakata, Akira Matsumoto, Madoka Takai, Kazuhiko Ishihara, Yuji Miyahara, “Phospholipid polymer-modified field effect transistor for sensitive detection of biomolecular recognition”, MRS2008, 2008/12/2.
  49. Takashi Chin, Toshiya Sakata, Akira Matsumoto, Madoka Takai, Kazuhiko Ishihara, Yuji Miyahara, “Chemically-Functionalized Biotransistor for Noninvasive and High-throughput Monitoring of Apoptosis”, MRS2008, 2008/12/2.
  50. Toshiya Sakata, “Field Effect-Based Biosensing Devices for Cell Functional Analysis”, MRS2008, 2008/12/2.
  51. Taiichiro Murakami, Toshiya Sakata, Akira Matsumoto, Madoka Takai, Kazuhiko Ishihara, Yuji Miyahara, “Development of Bio/Transistor Interface for Highly Sensitive Detection of Ion channel Behavior at Cell Membrane”, MNC2008, 2008/10/29.
  52. Toshiya Sakata, “Field-effect biosensing devices for bio-functional analysis”, NanoBio Seoul 2008, 2008/10/30-31.
  53. Takanori Shirai, Toshiya Sakata, Madoka Takai, Yuji Miyahara, Kazuhiko Ishihara, “MICROCHIP ANALYSIS OF CELLULAR RESPIRATORY ACTIVITY ON PDMS MEMBRANE HAVING GAS PERMSELECTIVE PROPERTY”, μTAS2008, 2008/10/15.
  54. Toshiya Sakata, Yuji Miyahara, “Noninvasive monitoring of transporter-substrate interaction at cell membrane using semiconductor devices”, ACS2008, 2008/8/17.
  55. Toshiya Sakata, Yuji Miyahara, “Field Effect-Based Biosensing Device for Bio-Functional Analysis”, Biosensors2008, 2008/5/16.
  56. Toshiya Sakata, Yuji Miyahara, “Field Effect-Based DNA Sequencing”, Biosensors2008, 2008/5/16.
  57. Toshiya Sakata and Yuji Miyahara, “Drug transport measurement for transporter variants using oocyte-based field effect transistor”, MNC2007, Japan Society of Applied Physics, 2007/11/8.
  58. Toshiya Sakata, “Cell-based Field Effect Devices for Cell Functional Analysis”, Micro and Nano Engineering (MNE) 2007 (Copenhagen), 2007/9/24.
  59. Toshiya Sakata and Yuji Miyahara, “Potentiometric drug transport analysis using oocyte-based field effect transistor”, microTAS2006, 2006/11/5-9.
  60. Toshiya Sakata, Aiko Ueda and Yuji Miyahara, “Cell-based field effect devices for cell functional analysis-electrical detection of glucose-induced insulin secretion for pancreatic beta cell-”, MNC2006, Japan Society of Applied Physics, 2006/10/25-27.
  61. Toshiya Sakata and Yuji Miyahara, “Genetic field effect devices for DNA analysis”, IEEE SENSORS 2006, Korea, 2006/10/22-25.
  62. Toshiya Sakata and Yuji Miyahara, “Fundamental Study on Drug Transport Using Oocyte Field Effect Transistor”, APCOT2006, Singapore, 2006/6/27.
  63. Yuji Miyahara and Toshiya Sakata, “pH Response of EIS Field Effect Device with Nano-pillar Structure”, APCOT2006, Singapore, 2006/6/27.
  64. Toshiya Sakata and Yuji Miyahara, “Cell-based field effect devices for cell adhesion analysis”, MMB2006, Okinawa, 2006/5/10-11.
  65. Toshiya Sakata and Yuji Miyahara, “Detection sensitivity of genetic field effect transistor combined with charged nanoparticle-DNA conjugate”, MMB2006, Okinawa, 2006/5/10-11.
  66. Yuji Miyahara and Toshiya Sakata, “Label-free electrostatic detection of biomolecular recognition using field effect transistor”, International Symposium on Molecular Scale Electronics Nanotechnology Research Institute, Japan 2005/12/5-6.
  67. Yuji Miyahara and Toshiya Sakata, “Potentiometric detection of DNA molecular recognition using genetic field effect transistor”, International Conference on Electrochemical Sensors, Budapest, 2005/11/13-19.
  68. Toshiya Sakata and Yuji Miyahara, “Potential Response of Genetic Field Effect Transistor to Charged Nanoparticle-DNA Conjugate”, MNC2005, Japan, 2005/10/25-28.
  69. Yuji Miyahara and Toshiya Sakata, “Cell-based field effect devices for cell adhesion analysis”, microTAS2005, 2005/10/9-13.
  70. Toshiya Sakata and Yuji Miyahara, “DNA Analysis Using Genetic Field Effect Transistor”, 6th International Conference on Intelligent Materials and System, Japan, 2005/7/4-6.
  71. Toshiya Sakata and Yuji Miyahara, “DNA Sequencing Using Genetic Field Effect Transistor”, Transducers’05, Korea, 2005/6/5-9.
  72. Toshiya Sakata and Yuji Miyahara, “Direct Detection of Single-Base Extension Reaction Using Genetic Field Effect Transistor”, 3rd International IEEE EMBS Special Topics Conference on Microte, Hawaii, 2005/5/12-14.
  73. Toshiya Sakata, Sumio Maruyama, Hidenori Otsuka and Yuji Miyahara, “Tripodal Thiol-Derivatives as a Functional Interface Monolayer for Immobilization of Biomolecules”, Hawaii, 2005/5/12-14.
  74. Toshiya Sakata and Yuji Miyahara, “Direct Detection of Single Nucleotide Polymorphism Using Genetic Field Effect Transistor, MNC2004, 2004/10/28.
  75. Toshiya Sakata and Yuji Miyahara, “Genetic Field Effect Transistor for SNP Analysis”, CHIPS TO HITS, Boston, 2004/9/20-23.
  76. Toshiya Sakata and Yuji Miyahara, “Potentiometric Detection of Allele Specific Oligonucleotide Hybridization Using Genetic Field Effect Transistor”, Asia-Pacific Conference of Transducers and Micro-Nano Technology (APCOT MNT 2004), Sapporo, (2004).
  77. Toshiya Sakata and Yuji Miyahara, “Direct Transduction of Oligonucleotide Extension into Electrical Signal Using Genetic Field Effect Transistor”, Asia-Pacific Conference of Transducers and Micro-Nano Technology (APCOT MNT 2004), Sapporo, (2004).
  78. Toshiya Sakata, Shinya Matsumoto, Yoshio Nakajima and Yuji Miyahara, “Potential behavior of bio-chemically modified gold electrode for extended gate field effect transistor”, Asia-Pacific Conference of Transducers and Micro-Nano Technology (APCOT MNT 2004), Sapporo, (2004).
  79. Toshiya Sakata and Yuji Miyahara, “Potentiometric Detection of Allele Specific Oligonucleotide Hybridization Using Genetic Field Effect Transistor”, Micro-Total-Analysis-System (m-TAS), Sweden, (2004).
  80. Toshiya Sakata and Yuji Miyahara, “Direct Transduction of Oligonucleotide Extension into Electrical Signal Using Genetic Field Effect Transistor”, Micro-Total-Analysis-System (m-TAS), Sweden, (2004).
  81. Toshiya Sakata, Hidenori Otsuka and Yuji Miyahara, “Potentiometric detection of DNA molecules hybridization using genetic field effect transistor and intercalator”, Material Research Society (MRS) Symp., Boston, (2003).
  82. Toshiya Sakata, Hidenori Otsuka and Yuji Miyahara, “Detection of DNA Molecules Using Insulated Gate Field Effect Transistor and Intercalator”, Solid State Devices and Materials (SSDM), Tokyo, (2003).
  83. Toshiya Sakata, Hiroyuki Yasuda and Yukichi Umakoshi, “Effect of interphase boundary character on mechanical properties in NiAl(b) bicrystals with Ni3Al(g’) precipitates along grain boundary”, Material Research Society (MRS) Symp., Boston, (2002).
  84. Toshiya Sakata, Hiroyuki Yasuda and Yukichi Umakoshi, “Control of microstructure and crystal orientation distribution in NiAl-based (b/g’) two phase alloys by thermomachanical processing”, The Fourth Pacific Rim International Conference on Advanced Materials and Processing (PRICM4), Hawaii, (2001).

Patents

Over 10 patents have been accepted.

Press

(1) 2010.4.2
“Side Effect Analysis for Whole Cell” in Nikkei Sangyo Newspaper
(2) 2009.9.1
“ Novel biosensing technology for assisted reproductive technology”, press preview by The Japan Society of Applied Physics.
(3) 2009.8.10
“Embryo Sensor” in Nikkei Sangyo Newspaper

Department of Materials Engineering, School of Engineering The University of Tokyo

7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 Japan

Phone & Fax:+81-3-5841-1842
e-mail:biofet@biofet.t.u-tokyo.ac.jp / sakata@biofet.t.u-tokyo.ac.jpMAP